Science Question on Karyotypes

No specific reason for this, just popped into my head this morning.

I’ve read somewhere (probably Terry Pratchett somewhere) that there are 12 viable human karyotypes. I assume this refers solely to the sex chromosomes as well. Looking at Wikipedia I can see some of them. Now, by viable I mean just capable of living, not necessarily of breeding.

OK, we all know XX and XY, I assume most have heard of XXY and XYY, XO is new to me and apparently YO never happens. I can imagine that XXX happens and that YY and YYY do not for the same reason YO doesn’t.

So that’s six possibilities. What are the other 6? Any ideas?

2 responses

  1. Peter Metcalfe Avatar
    Peter Metcalfe

    Down’s syndrome plus each of the sexual karyotypes would give another six.

  2. John Thacker Avatar
    John Thacker

    XXYY apparently occurs as well and is viable. No one can survive without an X chromosome, yes.

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